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IsoMiRmap: fast, deterministic and exhaustive mining of isomiRs from short RNA-seq datasets

MOTIVATION: MicroRNA (miRNA) precursor arms give rise to multiple isoforms simultaneously called ‘isomiRs.’ IsomiRs from the same arm typically differ by a few nucleotides at either their 5′ or 3′ termini or both. In humans, the identities and abundances of isomiRs depend on a person’s sex and genet...

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Detalles Bibliográficos
Autores principales: Loher, Phillipe, Karathanasis, Nestoras, Londin, Eric, F. Bray, Paul, Pliatsika, Venetia, Telonis, Aristeidis G., Rigoutsos, Isidore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317110/
https://www.ncbi.nlm.nih.gov/pubmed/33471076
http://dx.doi.org/10.1093/bioinformatics/btab016