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Inhibition of mTOR signaling by rapamycin protects photoreceptors from degeneration in rd1 mice

Retinitis pigmentosa (RP) is an inherited retinal degenerative disease that begins with defective rod photoreceptor function, followed by impaired cone function, and complete blindness in its late stage. To date, however, there is no effective treatment for RP. By carrying a nonsense mutation in the...

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Detalles Bibliográficos
Autores principales: Yang, Jia-Liang, Zou, Tong-Dan, Yang, Fang, Yang, Zheng-Lin, Zhang, Hou-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317187/
https://www.ncbi.nlm.nih.gov/pubmed/34235896
http://dx.doi.org/10.24272/j.issn.2095-8137.2021.049