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Characterization of DNA lesions associated with cell-free DNA by targeted deep sequencing

BACKGROUND: Recently, a next-generation sequencing (NGS)-based method has been used for the successful detection of circulating tumor DNA (ctDNA) in various cancer types. Thus, the use of NGS on liquid biopsies will improve cancer diagnosis and prognosis. However, the low-allelic fraction of ctDNA p...

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Detalles Bibliográficos
Autores principales: Shin, Seung-Ho, Park, Woong-Yang, Park, Donghyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317339/
https://www.ncbi.nlm.nih.gov/pubmed/34320984
http://dx.doi.org/10.1186/s12920-021-01040-8