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Characterization of DNA lesions associated with cell-free DNA by targeted deep sequencing
BACKGROUND: Recently, a next-generation sequencing (NGS)-based method has been used for the successful detection of circulating tumor DNA (ctDNA) in various cancer types. Thus, the use of NGS on liquid biopsies will improve cancer diagnosis and prognosis. However, the low-allelic fraction of ctDNA p...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317339/ https://www.ncbi.nlm.nih.gov/pubmed/34320984 http://dx.doi.org/10.1186/s12920-021-01040-8 |