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Decreased prevalence of the Plasmodium falciparum Pfcrt K76T and Pfmdr1 and N86Y mutations post-chloroquine treatment withdrawal in Katete District, Eastern Zambia

BACKGROUND: In 2002, Zambia withdrew chloroquine as first-line treatment for Plasmodium falciparum malaria due to increased treatment failure and worldwide spread of chloroquine resistance. The artemisinin combination regimen, artemether–lumefantrine, replaced chloroquine (CQ) as first choice malari...

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Detalles Bibliográficos
Autores principales: Mulenga, Mwenda C., Sitali, Lungowe, Ciubotariu, Ilinca I., Hawela, Moonga B., Hamainza, Busiku, Chipeta, James, Mharakurwa, Sungano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317340/
https://www.ncbi.nlm.nih.gov/pubmed/34320992
http://dx.doi.org/10.1186/s12936-021-03859-z