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Cell fusion enhances energy metabolism of mesenchymal tumor hybrid cells to sustain their proliferation and invasion

BACKGROUND: Cell-to-cell fusion is emerging as a key element of the metastatic process in various cancer types. We recently showed that hybrids made from the spontaneous merging of pre-malignant (IMR90 E6E7, i.e. E6E7) and malignant (IMR90 E6E7 RST, i.e. RST) mesenchymal cells recapitulate the main...

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Detalles Bibliográficos
Autores principales: Brito, Ariadna, Merle, Candice, Lagarde, Pauline, Faustin, Benjamin, Devin, Anne, Lartigue, Lydia, Chibon, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317390/
https://www.ncbi.nlm.nih.gov/pubmed/34320948
http://dx.doi.org/10.1186/s12885-021-08561-6