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Induction of colorectal carcinogenesis in the C57BL/6J and A/J mouse strains with a reduced DSS dose in the AOM/DSS model

BACKGROUND: Colorectal cancer (CRC) is one of the most frequently diagnosed cancers worldwide and thus mouse models of CRC are of significant value to study the pathogenesis. The Azoxymethane/Dextran sulfate sodium (AOM/DSS) model is a widely used, robust initiation-promotion model for chemical indu...

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Detalles Bibliográficos
Autores principales: Arnesen, Henriette, Müller, Mette Helen Bjørge, Aleksandersen, Mona, Østby, Gunn Charlotte, Carlsen, Harald, Paulsen, Jan Erik, Boysen, Preben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317392/
https://www.ncbi.nlm.nih.gov/pubmed/34315530
http://dx.doi.org/10.1186/s42826-021-00096-y