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Analysis of conventional and alternative CRISPR/Cas9 genome editing to enhance a single-base pair knock-in mutation

BACKGROUND: The use of CRISPR/Cas9 technologies in generating single-base pair knock-in mutations has recently exploded in the number of methods available. However, with the growing expansion of new technologies, it can be difficult to determine the best method for genome editing. RESULTS: In this s...

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Detalles Bibliográficos
Autores principales: Edmondson, Carina, Zhou, Qi, Liu, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317408/
https://www.ncbi.nlm.nih.gov/pubmed/34315458
http://dx.doi.org/10.1186/s12896-021-00707-5