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Sublethal doxorubicin promotes migration and invasion of breast cancer cells: role of Src Family non-receptor tyrosine kinases

BACKGROUND: Doxorubicin (Dox) is a widely used chemotherapy, but its effectiveness is limited by dose-dependent side effects. Although lower Dox doses reduce this risk, studies have reported higher recurrence of local disease with no improvement in survival rate in patients receiving low doses of Do...

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Detalles Bibliográficos
Autores principales: Mohammed, Samia, Shamseddine, Achraf A., Newcomb, Benjamin, Chavez, Ronald S., Panzner, Tyler D., Lee, Allen H., Canals, Daniel, Okeoma, Chioma M., Clarke, Christopher J., Hannun, Yusuf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317414/
https://www.ncbi.nlm.nih.gov/pubmed/34315513
http://dx.doi.org/10.1186/s13058-021-01452-5