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Spatial epi-proteomics enabled by histone post-translational modification analysis from low-abundance clinical samples
BACKGROUND: Increasing evidence linking epigenetic mechanisms and different diseases, including cancer, has prompted in the last 15 years the investigation of histone post-translational modifications (PTMs) in clinical samples. Methods allowing the isolation of histones from patient samples followed...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317427/ https://www.ncbi.nlm.nih.gov/pubmed/34315505 http://dx.doi.org/10.1186/s13148-021-01120-7 |