Cargando…

Spatial epi-proteomics enabled by histone post-translational modification analysis from low-abundance clinical samples

BACKGROUND: Increasing evidence linking epigenetic mechanisms and different diseases, including cancer, has prompted in the last 15 years the investigation of histone post-translational modifications (PTMs) in clinical samples. Methods allowing the isolation of histones from patient samples followed...

Descripción completa

Detalles Bibliográficos
Autores principales: Noberini, Roberta, Savoia, Evelyn Oliva, Brandini, Stefania, Greco, Francesco, Marra, Francesca, Bertalot, Giovanni, Pruneri, Giancarlo, McDonnell, Liam A., Bonaldi, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317427/
https://www.ncbi.nlm.nih.gov/pubmed/34315505
http://dx.doi.org/10.1186/s13148-021-01120-7