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Spatial epi-proteomics enabled by histone post-translational modification analysis from low-abundance clinical samples

BACKGROUND: Increasing evidence linking epigenetic mechanisms and different diseases, including cancer, has prompted in the last 15 years the investigation of histone post-translational modifications (PTMs) in clinical samples. Methods allowing the isolation of histones from patient samples followed...

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Detalles Bibliográficos
Autores principales:	Noberini, Roberta, Savoia, Evelyn Oliva, Brandini, Stefania, Greco, Francesco, Marra, Francesca, Bertalot, Giovanni, Pruneri, Giancarlo, McDonnell, Liam A., Bonaldi, Tiziana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317427/ https://www.ncbi.nlm.nih.gov/pubmed/34315505 http://dx.doi.org/10.1186/s13148-021-01120-7

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