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Gasdermin E-mediated programmed cell death: An unpaved path to tumor suppression

Hearing loss-associated protein gasdermin E (GSDME), an effector of secondary necrosis, has been identified in a new pathway of programmed cell death (PCD). GSDME epigenetic silencing and mutations resulting in loss-of-function have been reported in cancer tissues. Additionally, GSDME upregulation i...

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Detalles Bibliográficos
Autores principales: Wang, Yueyuan, Peng, Jingyu, Xie, Xiao, Zhang, Zhihao, Li, Mingxi, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317517/
https://www.ncbi.nlm.nih.gov/pubmed/34335940
http://dx.doi.org/10.7150/jca.48989