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Trop2 binding IGF2R induces gefitinib resistance in NSCLC by remodeling the tumor microenvironment
Gefitinib has shown good efficacy in treating recurrent or advanced non-small cell lung cancer (NSCLC), but the drug resistance remains a clinical challenge in medical oncology. In addition, the complex interaction between tumor cells and heterogeneous stromal cells in the adjacent tumor microenviro...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317539/ https://www.ncbi.nlm.nih.gov/pubmed/34335947 http://dx.doi.org/10.7150/jca.57711 |