Calcium-Sensing Receptors Control CYP27B1-Luciferase Expression: Transcriptional and Posttranscriptional Mechanisms

25-hydroxyvitamin D 1α-hydroxylase (encoded by CYP27B1), which catalyzes the synthesis of 1,25-dihydroxyvitamin D(3), is subject to negative or positive modulation by extracellular Ca(2+) (Ca(2+)(o)) depending on the tissue. However, the Ca(2+) sensors and underlying mechanisms are unidentified. We...

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Detalles Bibliográficos
Autores principales: Huang, Alice, Binmahfouz, Lenah, Hancock, Dale P, Anderson, Paul H, Ward, Donald T, Conigrave, Arthur D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317635/
https://www.ncbi.nlm.nih.gov/pubmed/34337274
http://dx.doi.org/10.1210/jendso/bvab057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317635/
https://www.ncbi.nlm.nih.gov/pubmed/34337274
http://dx.doi.org/10.1210/jendso/bvab057

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