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Calcium-Sensing Receptors Control CYP27B1-Luciferase Expression: Transcriptional and Posttranscriptional Mechanisms
25-hydroxyvitamin D 1α-hydroxylase (encoded by CYP27B1), which catalyzes the synthesis of 1,25-dihydroxyvitamin D(3), is subject to negative or positive modulation by extracellular Ca(2+) (Ca(2+)(o)) depending on the tissue. However, the Ca(2+) sensors and underlying mechanisms are unidentified. We...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317635/ https://www.ncbi.nlm.nih.gov/pubmed/34337274 http://dx.doi.org/10.1210/jendso/bvab057 |