Chemical synthesis of stimuli-responsive guide RNA for conditional control of CRISPR-Cas9 gene editing

CRISPR-Cas9 promotes changes in identity or abundance of nucleic acids in live cells and is a programmable modality of broad biotechnological and therapeutic interest. To reduce off-target effects, tools for conditional control of CRISPR-Cas9 functions are under active research, such as stimuli-resp...

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Detalles Bibliográficos
Autores principales: Gu, Chunmei, Xiao, Lu, Shang, Jiachen, Xu, Xiao, He, Luo, Xiang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317661/
https://www.ncbi.nlm.nih.gov/pubmed/34377390
http://dx.doi.org/10.1039/d1sc01194d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317661/
https://www.ncbi.nlm.nih.gov/pubmed/34377390
http://dx.doi.org/10.1039/d1sc01194d

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