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Chemical synthesis of stimuli-responsive guide RNA for conditional control of CRISPR-Cas9 gene editing
CRISPR-Cas9 promotes changes in identity or abundance of nucleic acids in live cells and is a programmable modality of broad biotechnological and therapeutic interest. To reduce off-target effects, tools for conditional control of CRISPR-Cas9 functions are under active research, such as stimuli-resp...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317661/ https://www.ncbi.nlm.nih.gov/pubmed/34377390 http://dx.doi.org/10.1039/d1sc01194d |