Analysis of Prostate Cancer Tumor Microenvironment Identifies Reduced Stromal CD4 Effector T-cell Infiltration in Tumors with Pelvic Nodal Metastasis

BACKGROUND: Pelvic nodal metastasis in prostate cancer impacts patient outcome negatively. OBJECTIVE: To explore tumor-infiltrating immune cells as a potential predictive tool for regional lymph node (LN) metastasis. DESIGN, SETTING, AND PARTICIPANTS: We applied multiplex immunofluorescence and targ...

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Detalles Bibliográficos
Autores principales: Ntala, Chara, Salji, Mark, Salmond, Jonathan, Officer, Leah, Teodosio, Ana Vieira, Blomme, Arnaud, McGhee, Ewan J., Powley, Ian, Ahmad, Imran, Kruithof-de Julio, Marianna, Thalmann, George, Roberts, Ed, Goodyear, Carl S., Jamaspishvili, Tamara, Berman, David M., Carlin, Leo M., Le Quesne, John, Leung, Hing Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Prostate Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317840/
https://www.ncbi.nlm.nih.gov/pubmed/34337530
http://dx.doi.org/10.1016/j.euros.2021.05.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317840/
https://www.ncbi.nlm.nih.gov/pubmed/34337530
http://dx.doi.org/10.1016/j.euros.2021.05.001

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