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Delineating the Ligand–Receptor Interactions That Lead to Biased Signaling at the μ-Opioid Receptor
[Image: see text] Biased agonists, which selectively stimulate certain signaling pathways controlled by a G protein-coupled receptor (GPCR), hold great promise as drugs that maximize efficacy while minimizing dangerous side effects. Biased agonists of the μ-opioid receptor (μOR) are of particular in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317888/ https://www.ncbi.nlm.nih.gov/pubmed/34251810 http://dx.doi.org/10.1021/acs.jcim.1c00585 |