Protective Effects of Dexazoxane on Rat Ferroptosis in Doxorubicin-Induced Cardiomyopathy Through Regulating HMGB1

Dexrazoxane (DXZ) reduces cytotoxicity caused by Doxorubicin (DOX). However, the mechanism of DXZ in ferroptosis and cardiomyopathy remains unclear. This research, therefore, explores the role and mechanism of DXZ in DOX-induced ferroptosis and cardiomyopathy in rats. Kaplan–Meier survival analysis...

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Detalles Bibliográficos
Autores principales: Zhang, Haiyan, Wang, Zheng, Liu, Zhengxia, Du, Kang, Lu, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318065/
https://www.ncbi.nlm.nih.gov/pubmed/34336950
http://dx.doi.org/10.3389/fcvm.2021.685434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318065/
https://www.ncbi.nlm.nih.gov/pubmed/34336950
http://dx.doi.org/10.3389/fcvm.2021.685434

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