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Ubiquitin‐proteasome‐system and enzymes of energy metabolism in skeletal muscle of patients with HFpEF and HFrEF

BACKGROUND: Skeletal muscle (SM) alterations contribute to exercise intolerance in heart failure patients with preserved (HFpEF) or reduced (HFrEF) left ventricular ejection fraction (LVEF). Protein degradation via the ubiquitin‐proteasome‐system (UPS), nuclear apoptosis, and reduced mitochondrial e...

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Detalles Bibliográficos
Autores principales: Adams, Volker, Wunderlich, Sebastian, Mangner, Norman, Hommel, Jennifer, Esefeld, Katrin, Gielen, Stephan, Halle, Martin, Ellingsen, Øyvind, Van Craenenbroeck, Emeline M., Wisløff, Ulrik, Pieske, Burkert, Linke, Axel, Winzer, Ephraim B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318515/
https://www.ncbi.nlm.nih.gov/pubmed/33955206
http://dx.doi.org/10.1002/ehf2.13405