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Sensitivity Assessment of Wilms Tumor Gene (WT1) Expression in Glioblastoma using qPCR and Immunohistochemistry and its Association with IDH1 Mutation and Recurrence Interval

PURPOSE: Wilms tumor 1 (WT1) gene has recently shown a role in gliomagenesis, making it a potential immunotherapy target in glioblastomas. We aimed to investigate the most sensitive method to detect WT1 expression in glioblastoma and explore the relationship between WT1 expression, IDH1 mutation and...

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Detalles Bibliográficos
Autores principales: Kurdi, Maher, Butt, Nadeem Shafique, Baeesa, Saleh, Kuerban, Abudukadeer, Maghrabi, Yazid, Bardeesi, Anas, Saeedi, Rothaina, Alghamdi, Badrah S, Lary, Ahmed I, Mohamed, Fawaz, Hakamy, Sahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318730/
https://www.ncbi.nlm.nih.gov/pubmed/34335021
http://dx.doi.org/10.2147/BTT.S323358