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p53 Deacetylation Alleviates Sepsis-Induced Acute Kidney Injury by Promoting Autophagy

Recent studies have shown that autophagy upregulation can attenuate sepsis-induced acute kidney injury (SAKI). The tumor suppressor p53 has emerged as an autophagy regulator in various forms of acute kidney injury (AKI). Our previous studies showed that p53 acetylation exacerbated hemorrhagic shock-...

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Detalles Bibliográficos
Autores principales: Sun, Maomao, Li, Jiaxin, Mao, Liangfeng, Wu, Jie, Deng, Zhiya, He, Man, An, Sheng, Zeng, Zhenhua, Huang, Qiaobing, Chen, Zhongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318785/
https://www.ncbi.nlm.nih.gov/pubmed/34335587
http://dx.doi.org/10.3389/fimmu.2021.685523