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T-cells in chronic lymphocytic leukemia: Guardians or drivers of disease?

Chronic lymphocytic leukemia (CLL) is a B-cell malignancy, which is associated with profound alterations and defects in the immune system and a prevalent dependency on the microenvironmental niche. An abnormal T-cell compartment in the blood of CLL patients was already reported 40 years ago. Since t...

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Detalles Bibliográficos
Autores principales: Roessner, Philipp M., Seiffert, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318881/
https://www.ncbi.nlm.nih.gov/pubmed/32457353
http://dx.doi.org/10.1038/s41375-020-0873-2