Roles of the ubiquitin ligase CUL4B and ADP-ribosyltransferase TiPARP in TCDD-induced nuclear export and proteasomal degradation of the transcription factor AHR

The aryl hydrocarbon receptor (AHR) is a transcription factor activated by exogenous halogenated polycyclic aromatic hydrocarbon compounds, including the environmental toxin TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin, and naturally occurring dietary and endogenous compounds. The activated AHR enhance...

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Detalles Bibliográficos
Autores principales: Rijo, Mercedes Paz, Diani-Moore, Silvia, Yang, Chenyi, Zhou, Pengbo, Rifkind, Arleen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318916/
https://www.ncbi.nlm.nih.gov/pubmed/34146543
http://dx.doi.org/10.1016/j.jbc.2021.100886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318916/
https://www.ncbi.nlm.nih.gov/pubmed/34146543
http://dx.doi.org/10.1016/j.jbc.2021.100886

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