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Potential inhibitors of the main protease of SARS-CoV-2 and modulators of arachidonic acid pathway: Non-steroidal anti-inflammatory drugs against COVID-19

The main protease of SARS-CoV-2 is one of the key targets to develop and design antiviral drugs. There is no general agreement on the use of non-steroidal anti-inflammatory drugs (NSAIDs) in COVID-19. In this study, we investigated NSAIDs as potential inhibitors for chymotrypsin-like protease (3CLpr...

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Detalles Bibliográficos
Autores principales: Sisakht, Mohsen, Solhjoo, Aida, Mahmoodzadeh, Amir, Fathalipour, Mohammad, Kabiri, Maryam, Sakhteman, Amirhossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319042/
https://www.ncbi.nlm.nih.gov/pubmed/34340125
http://dx.doi.org/10.1016/j.compbiomed.2021.104686