PIK3R3, part of the regulatory domain of PI3K, is upregulated in sarcoma stem-like cells and promotes invasion, migration, and chemotherapy resistance

To identify drivers of sarcoma cancer stem-like cells (CSCs), we compared gene expression using RNA sequencing between HT1080 fibrosarcoma and SK-LMS-1 leiomyosarcoma spheroids (which are enriched for CSCs) compared with the parent populations. The most overexpressed survival signaling-related gene...

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Detalles Bibliográficos
Autores principales: Yoon, Changhwan, Lu, Jun, Ryeom, Sandra W., Simon, M. Celeste, Yoon, Sam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319167/
https://www.ncbi.nlm.nih.gov/pubmed/34321458
http://dx.doi.org/10.1038/s41419-021-04036-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319167/
https://www.ncbi.nlm.nih.gov/pubmed/34321458
http://dx.doi.org/10.1038/s41419-021-04036-5

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