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Human chromosome 3p21.3 carries TERT transcriptional regulators in pancreatic cancer

Frequent loss of heterozygosity (LOH) on the short arm of human chromosome 3 (3p) region has been found in pancreatic cancer (PC), which suggests the likely presence of tumor suppressor genes in this region. However, the functional significance of LOH in this region in the development of PC has not...

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Detalles Bibliográficos
Autores principales: Yagyu, Takuki, Ohira, Takahito, Shimizu, Ryutaro, Morimoto, Masaki, Murakami, Yuki, Hanaki, Takehiko, Kihara, Kyoichi, Matsunaga, Tomoyuki, Yamamoto, Manabu, Tokuyasu, Naruo, Sakamoto, Teruhisa, Fujiwara, Yoshiyuki, Kugoh, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319171/
https://www.ncbi.nlm.nih.gov/pubmed/34321527
http://dx.doi.org/10.1038/s41598-021-94711-6