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The effect of Quorum sensing inhibitors on the evolution of CRISPR-based phage immunity in Pseudomonas aeruginosa

Quorum sensing controls the expression of a wide range of important traits in the opportunistic pathogen Pseudomonas aeruginosa, including the expression of virulence genes and its CRISPR-cas immune system, which protects from bacteriophage (phage) infection. This finding has led to the speculation...

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Detalles Bibliográficos
Autores principales: Broniewski, Jenny M., Chisnall, Matthew A. W., Høyland-Kroghsbo, Nina Molin, Buckling, Angus, Westra, Edze R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319334/
https://www.ncbi.nlm.nih.gov/pubmed/33692485
http://dx.doi.org/10.1038/s41396-021-00946-6