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Exercise, programmed cell death and exhaustion of cardiomyocyte proliferation in aging zebrafish

Exercise may ameliorate the eventual heart failure inherent in human aging. In this study, we use zebrafish to understand how aging and exercise affect cardiomyocyte turnover and myocardial remodelling. We show that cardiomyocyte proliferation remains constant throughout life but that onset of fibro...

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Detalles Bibliográficos
Autores principales: Murphy, Lindsay B., Santos-Ledo, Adrian, Dhanaseelan, Tamilvendhan, Eley, Lorraine, Burns, David, Henderson, Deborah J., Chaudhry, Bill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319546/
https://www.ncbi.nlm.nih.gov/pubmed/34296752
http://dx.doi.org/10.1242/dmm.049013