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Exercise, programmed cell death and exhaustion of cardiomyocyte proliferation in aging zebrafish
Exercise may ameliorate the eventual heart failure inherent in human aging. In this study, we use zebrafish to understand how aging and exercise affect cardiomyocyte turnover and myocardial remodelling. We show that cardiomyocyte proliferation remains constant throughout life but that onset of fibro...
Autores principales: | Murphy, Lindsay B., Santos-Ledo, Adrian, Dhanaseelan, Tamilvendhan, Eley, Lorraine, Burns, David, Henderson, Deborah J., Chaudhry, Bill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319546/ https://www.ncbi.nlm.nih.gov/pubmed/34296752 http://dx.doi.org/10.1242/dmm.049013 |
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