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Transient, flexible gene editing in zebrafish neutrophils and macrophages for determination of cell-autonomous functions

Zebrafish are an important model for studying phagocyte function, but rigorous experimental systems to distinguish whether phagocyte-dependent effects are neutrophil or macrophage specific have been lacking. We have developed and validated transgenic lines that enable superior demonstration of cell-...

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Detalles Bibliográficos
Autores principales: Isiaku, Abdulsalam I., Zhang, Zuobing, Pazhakh, Vahid, Manley, Harriet R., Thompson, Ella R., Fox, Lucy C., Yerneni, Satwica, Blombery, Piers, Lieschke, Graham J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319549/
https://www.ncbi.nlm.nih.gov/pubmed/34296745
http://dx.doi.org/10.1242/dmm.047431