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Transient, flexible gene editing in zebrafish neutrophils and macrophages for determination of cell-autonomous functions
Zebrafish are an important model for studying phagocyte function, but rigorous experimental systems to distinguish whether phagocyte-dependent effects are neutrophil or macrophage specific have been lacking. We have developed and validated transgenic lines that enable superior demonstration of cell-...
Autores principales: | Isiaku, Abdulsalam I., Zhang, Zuobing, Pazhakh, Vahid, Manley, Harriet R., Thompson, Ella R., Fox, Lucy C., Yerneni, Satwica, Blombery, Piers, Lieschke, Graham J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319549/ https://www.ncbi.nlm.nih.gov/pubmed/34296745 http://dx.doi.org/10.1242/dmm.047431 |
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