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Loss of vacuolar-type H(+)-ATPase induces caspase-independent necrosis-like death of hair cells in zebrafish neuromasts
The vacuolar-type H(+)-ATPase (V-ATPase) is a multi-subunit proton pump that regulates cellular pH. V-ATPase activity modulates several cellular processes, but cell-type-specific functions remain poorly understood. Patients with mutations in specific V-ATPase subunits can develop sensorineural deafn...
Autores principales: | Santra, Peu, Amack, Jeffrey D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319552/ https://www.ncbi.nlm.nih.gov/pubmed/34296747 http://dx.doi.org/10.1242/dmm.048997 |
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