Combining Genome-Wide Gene Expression Analysis (RNA-seq) and a Gene Editing Platform (CRISPR-Cas9) to Uncover the Selectively Pro-oxidant Activity of Aurone Compounds Against Candida albicans

Candida albicans is the major fungal cause of healthcare-associated bloodstream infections worldwide with a 40% mortality rate. The scarcity of antifungal treatments due to the eukaryotic origin of fungal cells has challenged the development of selectively antifungal drugs. In an attempt to identify...

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Detalles Bibliográficos
Autores principales: Alqahtani, Fatmah M., Handy, Scott T., Sutton, Caleb L., Farone, Mary B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319688/
https://www.ncbi.nlm.nih.gov/pubmed/34335543
http://dx.doi.org/10.3389/fmicb.2021.708267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319688/
https://www.ncbi.nlm.nih.gov/pubmed/34335543
http://dx.doi.org/10.3389/fmicb.2021.708267

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