Cargando…

Estrogen Deficiency Induces Mitochondrial Damage Prior to Emergence of Cognitive Deficits in a Postmenopausal Mouse Model

Background: Estrogen deficiency contributes to the development of Alzheimer’s disease (AD) in menopausal women. In the current study, we examined the impact of estrogen deficiency on mitochondrial function and cognition using a postmenopausal mouse model. Methods: Bilateral ovariectomy was conducted...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Wei, Hou, Yue, Song, Xinxin, Wang, Lei, Zhang, Fangfang, Zhang, Hanting, Yu, Haiyang, Zhou, Yanmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319728/
https://www.ncbi.nlm.nih.gov/pubmed/34335235
http://dx.doi.org/10.3389/fnagi.2021.713819