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Estrogen Deficiency Induces Mitochondrial Damage Prior to Emergence of Cognitive Deficits in a Postmenopausal Mouse Model
Background: Estrogen deficiency contributes to the development of Alzheimer’s disease (AD) in menopausal women. In the current study, we examined the impact of estrogen deficiency on mitochondrial function and cognition using a postmenopausal mouse model. Methods: Bilateral ovariectomy was conducted...
Autores principales: | Zhao, Wei, Hou, Yue, Song, Xinxin, Wang, Lei, Zhang, Fangfang, Zhang, Hanting, Yu, Haiyang, Zhou, Yanmeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319728/ https://www.ncbi.nlm.nih.gov/pubmed/34335235 http://dx.doi.org/10.3389/fnagi.2021.713819 |
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