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Amyloid and Tau Induce Cell Death Independently of TSPO Polymerization and Density Changes

[Image: see text] Apoptosis-dependent cell death of astrocytes has been described in Alzheimer’s disease and is linked to the presence of two markers of the pathology: the β-amyloid peptide (Aβ) and the hyperphosphorylated Tau protein. Astrocytes also show reactive states characterized by the overex...

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Detalles Bibliográficos
Autores principales: Tournier, Benjamin B., Ceyzériat, Kelly, Bouteldja, Farha N., Millet, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319921/
https://www.ncbi.nlm.nih.gov/pubmed/34337211
http://dx.doi.org/10.1021/acsomega.1c01678