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Fully Automated Screening of a Combinatorial Library to Avoid False Positives: Application to Tetanus Toxoid Ligand Identification

[Image: see text] Peptide ligands are widely used in protein purification by affinity chromatography. Here, we applied a fully automated two-stage library screening method that avoids false positive peptidyl-bead selection and applied it to tetanus toxoid purification. The first library screening wa...

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Detalles Bibliográficos
Autores principales: Martínez Ceron, María C., Ávila, Lucía, Giudicessi, Silvana L., Minoia, Juan M., Fingermann, Matías, Camperi, Silvia A., Albericio, Fernando, Cascone, Osvaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319927/
https://www.ncbi.nlm.nih.gov/pubmed/34337215
http://dx.doi.org/10.1021/acsomega.1c01814