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Single Cell Transcriptomics of Ependymal Cells Across Age, Region and Species Reveals Cilia-Related and Metal Ion Regulatory Roles as Major Conserved Ependymal Cell Functions

Ependymal cells are ciliated-epithelial glial cells that develop from radial glia along the surface of the ventricles of the brain and the spinal canal. They play a critical role in cerebrospinal fluid (CSF) homeostasis, brain metabolism, and the clearance of waste from the brain. These cells have b...

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Detalles Bibliográficos
Autores principales: MacDonald, Adam, Lu, Brianna, Caron, Maxime, Caporicci-Dinucci, Nina, Hatrock, Dale, Petrecca, Kevin, Bourque, Guillaume, Stratton, Jo Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319996/
https://www.ncbi.nlm.nih.gov/pubmed/34335193
http://dx.doi.org/10.3389/fncel.2021.703951