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Age-related increase in caveolin-1 expression facilitates cell-to-cell transmission of α-synuclein in neurons

Parkinson's disease (PD) is the second most prevalent neurodegenerative disease, with aging being considered the greatest risk factor for developing PD. Caveolin-1 (Cav-1) is known to participate in the aging process. Recent evidence indicates that prion-like propagation of misfolded α-synuclei...

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Detalles Bibliográficos
Autores principales: Ha, Tae-Young, Choi, Yu Ree, Noh, Hye Rin, Cha, Seon-Heui, Kim, Jae-Bong, Park, Sang Myun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320051/
https://www.ncbi.nlm.nih.gov/pubmed/34321069
http://dx.doi.org/10.1186/s13041-021-00834-2