Cargando…

Age-related increase in caveolin-1 expression facilitates cell-to-cell transmission of α-synuclein in neurons

Parkinson's disease (PD) is the second most prevalent neurodegenerative disease, with aging being considered the greatest risk factor for developing PD. Caveolin-1 (Cav-1) is known to participate in the aging process. Recent evidence indicates that prion-like propagation of misfolded α-synuclei...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ha, Tae-Young, Choi, Yu Ree, Noh, Hye Rin, Cha, Seon-Heui, Kim, Jae-Bong, Park, Sang Myun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320051/ https://www.ncbi.nlm.nih.gov/pubmed/34321069 http://dx.doi.org/10.1186/s13041-021-00834-2

Ejemplares similares

Neuronal ApoE Regulates the Cell-to-Cell Transmission of α-Synuclein
por: Kang, Seo-Jun, et al.
Publicado: (2022)

Monitoring α-synuclein Aggregation Induced by Preformed α-synuclein Fibrils in an In Vitro Model System
por: Kim, Beom Jin, et al.
Publicado: (2023)

DJ-1 deficiency impairs glutamate uptake into astrocytes via the regulation of flotillin-1 and caveolin-1 expression
por: Kim, Jin-Mo, et al.
Publicado: (2016)

Loss of parkin promotes lipid rafts-dependent endocytosis through accumulating caveolin-1: implications for Parkinson’s disease
por: Cha, Seon-Heui, et al.
Publicado: (2015)

Caveolin-1 deficiency impairs synaptic transmission in hippocampal neurons
por: Koh, Soulmee, et al.
Publicado: (2021)

α-Synuclein and neuronal cell death
por: Cookson, Mark R
Publicado: (2009)

α-Synuclein and Neuronal Cell Death
por: Yasuda, Toru, et al.
Publicado: (2012)

Pathogenic Mutations Differentially Regulate Cell-to-Cell Transmission of α-Synuclein
por: Guan, Yuan, et al.
Publicado: (2020)

The role of quercetin on the survival of neuron-like PC12 cells and the expression of α-synuclein
por: Ahn, Tae-Beom, et al.
Publicado: (2015)

Therapeutic functions of astrocytes to treat α-synuclein pathology in Parkinson’s disease
por: Yang, Yunseon, et al.
Publicado: (2022)

Sex-dependent neuronal effects of α-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neurons
por: Santos, Altair Brito Dos, et al.
Publicado: (2023)

No apparent transmission of transgenic α–synuclein into nigrostriatal dopaminergic neurons in multiple mouse models
por: Sastry, Namratha, et al.
Publicado: (2015)

Binding of α-synuclein oligomers to Cx32 facilitates protein uptake and transfer in neurons and oligodendrocytes
por: Reyes, Juan F., et al.
Publicado: (2019)

Potential Modes of Intercellular α-Synuclein Transmission
por: Valdinocci, Dario, et al.
Publicado: (2017)

Amyloids of α-Synuclein Promote Chemical Transformations of Neuronal Cell Metabolites
por: Horvath, Istvan, et al.
Publicado: (2023)

Interaction between coxsackievirus B3 infection and α-synuclein in models of Parkinson’s disease
por: Park, Soo Jin, et al.
Publicado: (2021)

α-Synuclein Regulates Neuronal Cholesterol Efflux
por: Hsiao, Jen-Hsiang T., et al.
Publicado: (2017)

In situ architecture of neuronal α-Synuclein inclusions
por: Trinkaus, Victoria A., et al.
Publicado: (2021)

Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury
por: Ulusoy, Ayse, et al.
Publicado: (2015)

Oral and intravenous transmission of α-synuclein fibrils to mice
por: Lohmann, Stephanie, et al.
Publicado: (2019)

Nanoparticles With Affinity for α-Synuclein Sequester α-Synuclein to Form Toxic Aggregates in Neurons With Endolysosomal Impairment
por: Jiang, Peizhou, et al.
Publicado: (2021)

The couple of netrin-1/α-Synuclein regulates the survival of dopaminergic neurons via α-Synuclein disaggregation
por: Kang, Eun Ji, et al.
Publicado: (2023)

Expression of α-synuclein is regulated in a neuronal cell type-dependent manner
por: Taguchi, Katsutoshi, et al.
Publicado: (2018)

Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons
por: Ganjam, Goutham K., et al.
Publicado: (2019)

A dual role for α-synuclein in facilitation and depression of dopamine release from substantia nigra neurons in vivo
por: Somayaji, Mahalakshmi, et al.
Publicado: (2020)

Extracellular α-synuclein levels are regulated by neuronal activity
por: Yamada, Kaoru, et al.
Publicado: (2018)

Role of mitochondria in α-synuclein mediated neuronal toxicity
por: Pai, Sadashiva K.
Publicado: (2023)

Neuronal identity defines α-synuclein and tau toxicity
por: Praschberger, Roman, et al.
Publicado: (2023)

Uric acid regulates α-synuclein transmission in Parkinsonian models
por: Shin, Yu Jin, et al.
Publicado: (2023)

Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates
por: Bae, E-J, et al.
Publicado: (2015)

Exosomal cell-to-cell transmission of alpha synuclein oligomers
por: Danzer, Karin M, et al.
Publicado: (2012)

Cell Responses to Extracellular α-Synuclein
por: Surguchev, Alexei A., et al.
Publicado: (2019)

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death
por: Bourdenx, Mathieu, et al.
Publicado: (2014)

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells
por: Cascella, Roberta, et al.
Publicado: (2021)

Type-1 cannabinoid receptors colocalize with caveolin-1 in neuronal cells
por: Bari, Monica, et al.
Publicado: (2008)

Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils
por: Dhillon, Jess-Karan S., et al.
Publicado: (2019)

Conformational templating of α-synuclein aggregates in neuronal-glial cultures
por: Sacino, Amanda N, et al.
Publicado: (2013)

Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons
por: Urrea, Laura, et al.
Publicado: (2017)

Neuronal Oxidative Stress Promotes α-Synuclein Aggregation In Vivo
por: Won, Seok Joon, et al.
Publicado: (2022)

MhcII Regulates Transmission of α-Synuclein-Seeded Pathology in Mice
por: Gonzalez De La Cruz, Elsa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_874g2vbuufemu1ncjh69s3dh6b