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Combination chemoradiotherapy with temozolomide, vincristine, and interferon-β might improve outcomes regardless of O6-methyl-guanine-DNA-methyltransferase (MGMT) promoter methylation status in newly glioblastoma

BACKGROUND: This investigator-initiated, open-label, single-arm, single-institute study was conducted to investigate the effectiveness of induction combination chemoradiotherapy and long-term maintenance therapy with temozolomide (TMZ) plus interferon (IFN)-β for glioblastoma. METHODS: The initial i...

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Detalles Bibliográficos
Autores principales: Asano, Kenichiro, Fumoto, Toshio, Matsuzaka, Masashi, Hasegawa, Seiko, Suzuki, Naoya, Akasaka, Kenichi, Katayama, Kosuke, Kamataki, Akihisa, Kurose, Akira, Ohkuma, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320052/
https://www.ncbi.nlm.nih.gov/pubmed/34320929
http://dx.doi.org/10.1186/s12885-021-08592-z