Synthesis of Conformationally Liberated Yohimbine Analogues and Evaluation of Cytotoxic Activity

[Image: see text] A modular synthetic approach to strategically unique structural analogues of the alkaloid yohimbine is reported. The overall synthetic strategy couples the transition-metal-catalyzed decarboxylative allylation of 2,2-diphenylglycinate imino esters with a scandium triflate-mediated...

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Detalles Bibliográficos
Autores principales: Yang, Han, Poznik, Michal, Tang, Shaojian, Xue, Peng, Du, Lidong, Liu, Chenlu, Chen, Xiaochuan, Chruma, Jason J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320076/
https://www.ncbi.nlm.nih.gov/pubmed/34337266
http://dx.doi.org/10.1021/acsomega.1c02784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320076/
https://www.ncbi.nlm.nih.gov/pubmed/34337266
http://dx.doi.org/10.1021/acsomega.1c02784

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