Increased chitotriosidase 1 concentration following nusinersen treatment in spinal muscular atrophy

BACKGROUND: Studies regarding the impact of (neuro)inflammation and inflammatory response following repetitive, intrathecally administered antisense oligonucleotides (ASO) in 5q-associated spinal muscular atrophy (SMA) are sparse. Increased risk of hydrocephalus in untreated SMA patients and a margi...

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Detalles Bibliográficos
Autores principales: Freigang, Maren, Steinacker, Petra, Wurster, Claudia Diana, Schreiber-Katz, Olivia, Osmanovic, Alma, Petri, Susanne, Koch, Jan Christoph, Rostásy, Kevin, Falkenburger, Björn, Ludolph, Albert Christian, Otto, Markus, Hermann, Andreas, Günther, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320162/
https://www.ncbi.nlm.nih.gov/pubmed/34321067
http://dx.doi.org/10.1186/s13023-021-01961-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320162/
https://www.ncbi.nlm.nih.gov/pubmed/34321067
http://dx.doi.org/10.1186/s13023-021-01961-8

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