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Aorta-specific DNA methylation patterns in cell-free DNA from patients with bicuspid aortic valve-associated aortopathy

BACKGROUND: The dilation of the aorta that occurs as a consequence of a congenitally bicuspid aortic valve (BAV) is associated with a risk of dissection, aneurysm or rupture. With progressive aortopathy, surgery is often recommended, but current patient selection strategies have limitations. A blood...

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Detalles Bibliográficos
Autores principales: Maredia, Ashna, Guzzardi, David, Aleinati, Mohammad, Iqbal, Fatima, Khaira, Arshroop, Madhu, Aiswarya, Wang, Xuemei, Barker, Alex J., McCarthy, Patrick M., Fedak, Paul W. M., Greenway, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320174/
https://www.ncbi.nlm.nih.gov/pubmed/34321094
http://dx.doi.org/10.1186/s13148-021-01137-y