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Resveratrol protects human nucleus pulposus cells from degeneration by blocking IL-6/JAK/STAT3 pathway

BACKGROUND: Nucleus pulposus cells’ (NPCs’) degeneration is mainly responsible for the intervertebral disc degeneration (IDD), which is closely related to inflammatory response. Among the major proinflammatory factors that are related to NPCs’ degeneration, interleukin-6 (IL-6) and its downstream JA...

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Detalles Bibliográficos
Autores principales: Wu, Cenhao, Ge, Jun, Yang, Ming, Yan, Qi, Wang, Yingjie, Yu, Hao, Yang, Huilin, Zou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320225/
https://www.ncbi.nlm.nih.gov/pubmed/34321087
http://dx.doi.org/10.1186/s40001-021-00555-1