MYC suppresses STING-dependent innate immunity by transcriptionally upregulating DNMT1 in triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and lacks definite treatment targets. Tumor immune microenvironment (TIME) heterogeneity has a profound impact on the immunotherapy response. Tumors with non-inflamed TIME derive limited benefit from imm...

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Detalles Bibliográficos
Autores principales: Wu, Si-Yu, Xiao, Yi, Wei, Jin-Li, Xu, Xiao-En, Jin, Xi, Hu, Xin, Li, Da-Qiang, Jiang, Yi-Zhou, Shao, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320259/
https://www.ncbi.nlm.nih.gov/pubmed/34321275
http://dx.doi.org/10.1136/jitc-2021-002528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320259/
https://www.ncbi.nlm.nih.gov/pubmed/34321275
http://dx.doi.org/10.1136/jitc-2021-002528

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