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A Data-Driven Transcriptional Taxonomy of Adipogenic Chemicals to Identify White and Brite Adipogens
BACKGROUND: Chemicals in disparate structural classes activate specific subsets of the transcriptional programs of peroxisome proliferator-activated receptor- [Formula: see text] ([Formula: see text]) to generate adipocytes with distinct phenotypes. OBJECTIVES: Our objectives were to a) establish a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Environmental Health Perspectives
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320370/ https://www.ncbi.nlm.nih.gov/pubmed/34323617 http://dx.doi.org/10.1289/EHP6886 |