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A Data-Driven Transcriptional Taxonomy of Adipogenic Chemicals to Identify White and Brite Adipogens

BACKGROUND: Chemicals in disparate structural classes activate specific subsets of the transcriptional programs of peroxisome proliferator-activated receptor- [Formula: see text] ([Formula: see text]) to generate adipocytes with distinct phenotypes. OBJECTIVES: Our objectives were to a) establish a...

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Detalles Bibliográficos
Autores principales: Kim, Stephanie, Reed, Eric, Monti, Stefano, Schlezinger, Jennifer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320370/
https://www.ncbi.nlm.nih.gov/pubmed/34323617
http://dx.doi.org/10.1289/EHP6886