Development and Evaluation of a Droplet Digital PCR Assay for 8p23 β-Defensin Cluster Copy Number Determination

INTRODUCTION: It has been proposed that the copy number (CN) variation (CNV) in β-defensin genes (DEFB) on human chromosome 8p23 determines phenotypic differences in inflammatory diseases. However, no method for accurate and easy DEFB CN quantification is yet available. OBJECTIVE: Droplet digital po...

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Detalles Bibliográficos
Autores principales: Wen, Tingting, Zhang, Xianghong, Lippuner, Christoph, Schiff, Marcel, Stuber, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320422/
https://www.ncbi.nlm.nih.gov/pubmed/34327613
http://dx.doi.org/10.1007/s40291-021-00546-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320422/
https://www.ncbi.nlm.nih.gov/pubmed/34327613
http://dx.doi.org/10.1007/s40291-021-00546-2

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